Chillicothe, MO Weather Forecast | Local Weather Updates for Missouri by FOX Weather (2025)

Table of Contents

Chillicothe, MO Next 12 Hours Forecast in Chillicothe Hourly Weather Forecast & Temperature Latest Stories from Missouri Where does Helene go after hitting Florida? Southeast, mid-Atlantic could see 'catastrophic' flooding Fall begins with new storm to impact central US with severe weather, snow and flooding rain Caught on video: Fall severe weather produces tornado in northern Minnesota Viral TikTok challenge finds waterlily that holds more than 140 pounds References

U.S. / MO / Chillicothe / 64601

Chillicothe, MO

MO 64601 | 1:22pm

Weather Conditions

86°

Feels Like 86°

Sunny

57° 89°

UV Index

Good

Air Quality

SW 8 mph

Wind

0 in

rain

Today

Sat 10/12

89°

Highest Temperature

A mix of clouds and sun. Near record high temperatures. High 89F. Winds W at 5 to 10 mph.

Tonight

Sat 10/12

52°

Lowest Temperature

Partly cloudy skies. Low 52F. Winds light and variable.

Tomorrow

Sun 10/13

71°

Highest Temperature

Plentiful sunshine. High 71F. Winds NW at 10 to 20 mph.

Next 12 Hours Next 7 Days

Next 12 Hours Forecast in Chillicothe

Hourly Weather Forecast & Temperature

2PM

87°

Feels Like 87°

Mostly Sunny

WSW 8 mph

Wind

1011 mb

Pressure

36%

Humidity

UV Index

10mi

Visibility

25%

Cloud Cover

3PM

88°

Feels Like 88°

Mostly Sunny

WSW 9 mph

Wind

1010 mb

Pressure

33%

Humidity

UV Index

10mi

Visibility

28%

Cloud Cover

4PM

88°

Feels Like 88°

Partly Cloudy

WSW 9 mph

Wind

1009 mb

Pressure

33%

Humidity

UV Index

10mi

Visibility

31%

Cloud Cover

5PM

86°

Feels Like 86°

Partly Cloudy

W 8 mph

Wind

1009 mb

Pressure

34%

Humidity

UV Index

Latest Stories from Missouri

Where does Helene go after hitting Florida? Southeast, mid-Atlantic could see 'catastrophic' flooding

While Florida braces for Hurricane Helene, the size of the storm means widespread impacts will be felt across the eastern U.S. late this week, including damaging winds, flooding rain and possible tornadoes in states well into the Southeast, mid-Atlantic and Midwest after landfall.

Fall begins with new storm to impact central US with severe weather, snow and flooding rain

Right on time, the first fall storm of the season will bring cooler temperatures and crisper air to the Central U.S. after a dusting of snow in the Colorado Rockies over the weekend.

Caught on video: Fall severe weather produces tornado in northern Minnesota

Ahead of the severe weather, more than 4 million residents were put under alerts, including Severe Thunderstorm Watches and a Tornado Watch.

Viral TikTok challenge finds waterlily that holds more than 140 pounds

Missouri Botanical Garden in St. Louis was declared the winner, with their Victoria ‘Longwood Hybrid’ Waterlily holding 142.5 pounds of weight and measuring five feet in diameter.